| Fibrin-based biomaterials: modulation of macroscopic properties through rational design at the molecular level AC Brown, TH Barker Acta biomaterialia 10 (4), 1502-1514, 2014 | 288 | 2014 |
| Platelet mechanosensing of substrate stiffness during clot formation mediates adhesion, spreading, and activation Y Qiu, AC Brown, DR Myers, Y Sakurai, RG Mannino, R Tran, B Ahn, ... Proceedings of the National Academy of Sciences 111 (40), 14430-14435, 2014 | 213 | 2014 |
| Ultrasoft microgels displaying emergent platelet-like behaviours AC Brown, SE Stabenfeldt, B Ahn, RT Hannan, KS Dhada, ES Herman, ... Nature materials 13 (12), 1108-1114, 2014 | 205 | 2014 |
| Targeted repair of heart injury by stem cells fused with platelet nanovesicles J Tang, T Su, K Huang, PU Dinh, Z Wang, A Vandergriff, MT Hensley, ... Nature biomedical engineering 2 (1), 17-26, 2018 | 176 | 2018 |
| Physical and chemical microenvironmental cues orthogonally control the degree and duration of fibrosis‐associated epithelial‐to‐mesenchymal transitions AC Brown, VF Fiore, TA Sulchek, TH Barker The Journal of pathology 229 (1), 25-35, 2013 | 159 | 2013 |
| Single-platelet nanomechanics measured by high-throughput cytometry DR Myers, Y Qiu, ME Fay, M Tennenbaum, D Chester, J Cuadrado, ... Nature materials 16 (2), 230-235, 2017 | 113 | 2017 |
| The role of biophysical properties of provisional matrix proteins in wound repair D Chester, AC Brown Matrix Biology 60, 124-140, 2017 | 109 | 2017 |
| Ultrasoft, highly deformable microgels H Bachman, AC Brown, KC Clarke, KS Dhada, A Douglas, CE Hansen, ... Soft Matter 11 (10), 2018-2028, 2015 | 100 | 2015 |
| Inhalable dry powder mRNA vaccines based on extracellular vesicles KD Popowski, A Moatti, G Scull, D Silkstone, H Lutz, BL de Juan Abad, ... Matter 5 (9), 2960-2974, 2022 | 84 | 2022 |
| Chondroitin sulfate glycosaminoglycan hydrogels create endogenous niches for neural stem cells L Karumbaiah, SF Enam, AC Brown, T Saxena, MI Betancur, TH Barker, ... Bioconjugate chemistry 26 (12), 2336-2349, 2015 | 80 | 2015 |
| Targeted treatment of ischemic and fibrotic complications of myocardial infarction using a dual-delivery microgel therapeutic E Mihalko, K Huang, E Sproul, K Cheng, AC Brown ACS nano 12 (8), 7826-7837, 2018 | 72 | 2018 |
| Directing epithelial to mesenchymal transition through engineered microenvironments displaying orthogonal adhesive and mechanical cues MC Markowski, AC Brown, TH Barker Journal of biomedical materials research Part A 100 (8), 2119-2127, 2012 | 70 | 2012 |
| Learning from nature–novel synthetic biology approaches for biomaterial design AV Bryksin, AC Brown, MM Baksh, MG Finn, TH Barker Acta Biomaterialia 10 (4), 1761-1769, 2014 | 67 | 2014 |
| Continuously perfused, non-cross-contaminating microfluidic chamber array for studying cellular responses to orthogonal combinations of matrix and soluble signals ES Park, AC Brown, MA DiFeo, TH Barker, H Lu Lab on a Chip 10 (5), 571-580, 2010 | 66 | 2010 |
| Emerging concepts in engineering extracellular matrix variants for directing cell phenotype AE Carson, TH Barker Regenerative medicine 4 (4), 593-600, 2009 | 64 | 2009 |
| Detection of an integrin-binding mechanoswitch within fibronectin during tissue formation and fibrosis L Cao, J Nicosia, J Larouche, Y Zhang, H Bachman, AC Brown, ... ACS nano 11 (7), 7110-7117, 2017 | 63 | 2017 |
| Guiding epithelial cell phenotypes with engineered integrin-specific recombinant fibronectin fragments AC Brown, JA Rowe, TH Barker Tissue Engineering Part A 17 (1-2), 139-150, 2011 | 57 | 2011 |
| Platelet-like particles dynamically stiffen fibrin matrices and improve wound healing outcomes S Nandi, EP Sproul, K Nellenbach, M Erb, L Gaffney, DO Freytes, ... Biomaterials science 7 (2), 669-682, 2019 | 53 | 2019 |
| Integrin α3β1 binding to fibronectin is dependent on the ninth type III repeat AC Brown, MM Dysart, KC Clarke, SE Stabenfeldt, TH Barker Journal of Biological Chemistry 290 (42), 25534-25547, 2015 | 46 | 2015 |
| Platelet-mimetic strategies for modulating the wound environment and inflammatory responses S Nandi, AC Brown Experimental Biology and Medicine 241 (10), 1138-1148, 2016 | 45 | 2016 |
Thomas H. BarkerDepartment of Biomedical Engineering, University of VirginiaVerified email at virginia.edu
