Paul Germann
Paul Germann
Global Head Chemical & Preclinical Safety Merck KGaA; Prof.Dr. med vet habil.
Verified email at - Homepage
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Tumor necrosis factor-induced hepatocyte apoptosis precedes liver failure in experimental murine shock models.
M Leist, F Gantner, I Bohlinger, G Tiegs, PG Germann, A Wendel
The American journal of pathology 146 (5), 1220, 1995
Concanavalin A—induced T-cell—mediated hepatic injury in mice: the role of tumor necrosis factor
F Gantner, M Leist, AW Lohse, PG Germann, G Tiegs
Hepatology 21 (1), 190-198, 1995
Murine hepatocyte apoptosis induced in vitro and in vivo by TNF-alpha requires transcriptional arrest.
M Leist, F Gantner, I Bohlinger, PG Germann, G Tiegs, A Wendel
The Journal of Immunology 153 (4), 1778-1788, 1994
Models for open innovation in the pharmaceutical industry
A Schuhmacher, PG Germann, H Trill, O Gassmann
Drug discovery today 18 (23-24), 1133-1137, 2013
Endocrine system
CC Capen, E Karbe, U Deschl, C George, PG Germann, C Gopinath, ...
International Classification of Rodent Tumors. The Mouse, 269-322, 2001
Concanavalin A hepatotoxicity in mice: Tumor necrosis factor–mediated organ failure independent of caspase‐3–like protease activation
G Künstle, H Hentze, PG Germann, G Tiegs, T Meergans, A Wendel
Hepatology 30 (5), 1241-1251, 1999
Tumor necrosis factor-induced hepatic DNA fragmentation as an early marker of T cell-dependent liver injury in mice
F Gantner, M Leist, S Jilg, PG Germann, MA Freudenberg, G Tiegs
Gastroenterology 109 (1), 166-176, 1995
Effects of rSP-C surfactant on oxygenation and histology in a rat-lung-lavage model of acute lung injury
D Hafner, PG Germann, D Hauschke
American journal of respiratory and critical care medicine 158 (1), 270-278, 1998
Limited remyelination in Theiler's murine encephalomyelitis due to insufficient oligodendroglial differentiation of nerve/glial antigen 2 (NG2)‐positive putative …
R Ulrich, F Seeliger, M Kreutzer, PG Germann, W Baumgärtner
Neuropathology and applied neurobiology 34 (6), 603-620, 2008
Tumours by the intraperitoneal and intrapleural routes and their significance for the classification of mineral fibres
F Pott, M Roller, RM Rippe, PG Germann, B Bellmann
Mechanisms in fibre carcinogenesis, 547-565, 1991
Comparative carcinogenicity of cigarette mainstream and sidestream smoke condensates on the mouse skin
E Mohtashamipur, A Mohtashamipur, PG Germann, H Ernst, K Norpoth, ...
Journal of cancer research and clinical oncology 116 (6), 604-608, 1990
Effect of recombinant SP-C surfactant in a porcine lavage model of acute lung injury
RG Spragg, RM Smith, K Harris, J Lewis, D Hafner, P Germann
Journal of applied physiology 88 (2), 674-681, 2000
Characterizing “adversity” of pathology findings in nonclinical toxicity studies: Results from the 4th ESTP international expert workshop
X Palazzi, JE Burkhardt, H Caplain, V Dellarco, P Fant, JR Foster, ...
Toxicologic Pathology 44 (6), 810-824, 2016
Comparison of rSP‐C surfactant with natural and synthetic surfactants after late treatment in a rat model of the acute respiratory distress syndrome
D Häfner, PG Germann, D Hauschke
British journal of pharmacology 124 (6), 1083-1090, 1998
Lung tumours in rats after intratracheal instillation of dusts
F Pott, DL Dungworth, U Heinrich, H Muhle, K Kamino, PG Germann, ...
The Annals of Occupational Hygiene 38 (inhaled_particles_VII), 357-363, 1994
DNA vaccination with both the haemagglutinin and fusion proteins but not the nucleocapsid protein protects against experimental measles virus infection
B Schlereth, PG Germann, V ter Meulen, S Niewiesk
Journal of General Virology 81 (5), 1321-1325, 2000
New functional cell-culture approach to pulmonary carcinogenesis and toxicology
M Emura, M Riebe, A Ochiai, M Aufderheide, P Germann, U Mohr
Journal of cancer research and clinical oncology 116 (6), 557-562, 1990
A rat model of acute respiratory distress syndrome (ARDS): Part 1. Time dependency of histological and pathological changes
PG Germann, D Häfner
Journal of pharmacological and toxicological methods 40 (2), 101-107, 1998
Classification of neural tumors in laboratory rodents, emphasizing the rat
K Weber, RH Garman, PG Germann, JF Hardisty, G Krinke, P Millar, ...
Toxicologic pathology 39 (1), 129-151, 2011
Additive effects of phosphodiesterase-4 inhibition on effects of rSP-C surfactant
D Hafner, PG Germann
American Journal of Respiratory and Critical Care Medicine 161 (5), 1495-1500, 2000
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