| Cytotoxic T cells use mechanical force to potentiate target cell killing R Basu, BM Whitlock, J Husson, A Le Floc’h, W Jin, A Oyler-Yaniv, ... Cell 165 (1), 100-110, 2016 | 398 | 2016 |
| αEβ7 integrin interaction with E-cadherin promotes antitumor CTL activity by triggering lytic granule polarization and exocytosis AL Floc'h, A Jalil, I Vergnon, BLM Chansac, V Lazar, G Bismuth, ... The Journal of experimental medicine 204 (3), 559-570, 2007 | 305 | 2007 |
| Dual blockade of IL‐4 and IL‐13 with dupilumab, an IL‐4Rα antibody, is required to broadly inhibit type 2 inflammation A Le Floc’h, J Allinne, K Nagashima, G Scott, D Birchard, S Asrat, Y Bai, ... Allergy 75 (5), 1188-1204, 2020 | 257 | 2020 |
| IL-2–dependent tuning of NK cell sensitivity for target cells is controlled by regulatory T cells G Gasteiger, S Hemmers, MA Firth, A Le Floc’h, M Huse, JC Sun, ... Journal of Experimental Medicine 210 (6), 1167-1178, 2013 | 243 | 2013 |
| CD103 or LFA-1 engagement at the immune synapse between cytotoxic T cells and tumor cells promotes maturation and regulates T-cell effector functions K Franciszkiewicz, A Le Floc'h, M Boutet, I Vergnon, A Schmitt, ... Cancer research 73 (2), 617-628, 2013 | 190 | 2013 |
| Annular PIP3 accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse A Le Floc’h, Y Tanaka, NS Bantilan, G Voisinne, G Altan-Bonnet, Y Fukui, ... Journal of Experimental Medicine 210 (12), 2721-2737, 2013 | 134 | 2013 |
| Minimal engagement of CD103 on cytotoxic T lymphocytes with an e-Cadherin-Fc molecule triggers lytic granule polarization via a phospholipase cγ–dependent pathway AL Floc'h, A Jalil, K Franciszkiewicz, P Validire, I Vergnon, ... Cancer research 71 (2), 328-338, 2011 | 110 | 2011 |
| Intratumoral induction of CD103 triggers tumor-specific CTL function and CCR5-dependent T-cell retention K Franciszkiewicz, A Le Floc'h, A Jalil, F Vigant, T Robert, I Vergnon, ... Cancer research 69 (15), 6249-6255, 2009 | 99 | 2009 |
| Diacylglycerol kinase α establishes T cell polarity by shaping diacylglycerol accumulation at the immunological synapse A Chauveau, A Le Floc’h, NS Bantilan, GA Koretzky, M Huse Science signaling 7 (340), ra82-ra82, 2014 | 67 | 2014 |
| Molecular mechanisms and functional implications of polarized actin remodeling at the T cell immunological synapse A Le Floc’h, M Huse Cellular and molecular life sciences 72, 537-556, 2015 | 61 | 2015 |
| From lipid second messengers to molecular motors: microtubule‐organizing center reorientation in T cells M Huse, A Le Floc'h, X Liu Immunological reviews 256 (1), 95-106, 2013 | 43 | 2013 |
| IL-4 and IL-13, not eosinophils, drive type 2 airway inflammation, remodeling and lung function decline G Scott, S Asrat, J Allinne, WK Lim, K Nagashima, D Birchard, S Srivatsan, ... Cytokine 162, 156091, 2023 | 18 | 2023 |
| Blocking common γ chain cytokine signaling ameliorates T cell–mediated pathogenesis in disease models A Le Floc’h, K Nagashima, D Birchard, G Scott, LH Ben, D Ajithdoss, ... Science Translational Medicine 15 (678), eabo0205, 2023 | 7 | 2023 |
| Broader impact of IL-4Rα blockade than IL-5 blockade on mediators of type 2 inflammation and lung pathology in a house dust mite-induced asthma mouse model J Allinne, G Scott, D Birchard, S Asrat, K Nagashima, A Le Floc'h, ... C93. MECHANISMS OF AIRWAY INFLAMMATION IN ASTHMA AND COPD, A5555-A5555, 2019 | 6 | 2019 |
| Broader Impact of IL-4Ra Blockade Than IL-5 Blockade on Type 2 Inflammation J Allinne, G Scott, D Birchard, S Asrat, K Nagashima, A Le Floc’H, ... European Respiratory Journal 54 (suppl 63), 2019 | 1 | 2019 |
| Correction: Annular PIP3 accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse A Le Floc’h, Y Tanaka, NS Bantilan, G Voisinne, G Altan-Bonnet, Y Fukui, ... The Journal of Experimental Medicine 214 (4), 1203, 2017 | 1 | 2017 |
| Protocol for T-cell Adhesion Strength on Tumor Cells under Flow Conditions M Boutet, K Franciszkiewicz, A Le Floc’h, F Mami-Chouaib Bio-protocol 3 (20), e936-e936, 2013 | 1 | 2013 |
| Simultaneous Blockade of IL-4 and IL-13 Signaling With Dupilumab Attenuates Type 2 Inflammation and Airway Remodeling in a Mouse Model of Severe Airway Disease S Asrat, G Scott, S Srivatsan, LH Ben, D Birchard, W Lim, K Nagashima, ... C34. BIOLOGIC THERAPY IN THE FIGHT AGAINST ASTHMA AND ALLERGIC INFLAMMATION …, 2024 | | 2024 |
| Differential Regulation of the Type 2 Cytokines, IL-4 and IL-13, and the Alarmins, IL-33 and TSLPA, in Airway Inflammation and Remodeling S Asrat, S Srivatsan, B Buonagurio, K Nagashima, G Scott, K Gayvert, ... B31. AIRWAY EPITHELIAL INFLAMMATION AND DYSFUNCTION, A3276-A3276, 2024 | | 2024 |
| 208 IL-4 and IL-13 drive distinct and overlapping disease-associated signatures in cell types relevant to atopic dermatitis S Srivatsan, B Buonagurio, K Nagashima, S Asrat, WK Lim, A Le Floc’h, ... Journal of Investigative Dermatology 143 (11), S367, 2023 | | 2023 |
