| Tissue-specific regulation of cytochrome c by post-translational modifications: respiration, the mitochondrial membrane potential, ROS, and apoptosis HA Kalpage, V Bazylianska, MA Recanati, A Fite, J Liu, J Wan, N Mantena, ... The FASEB Journal 33 (2), 1540, 2019 | 188 | 2019 |
| Targeting multiple signaling pathways: the new approach to acute myeloid leukemia therapy JL Carter, K Hege, J Yang, HA Kalpage, Y Su, H Edwards, M Hüttemann, ... Signal transduction and targeted therapy 5 (1), 288, 2020 | 136 | 2020 |
| Tissue-and condition-specific isoforms of mammalian cytochrome c oxidase subunits: from function to human disease CA Sinkler, H Kalpage, J Shay, I Lee, MH Malek, LI Grossman, ... Oxidative medicine and cellular longevity 2017, 2017 | 111 | 2017 |
| Cytochrome c phosphorylation: Control of mitochondrial electron transport chain flux and apoptosis HA Kalpage, J Wan, PT Morse, MP Zurek, AA Turner, A Khobeir, N Yazdi, ... The international journal of biochemistry & cell biology 121, 105704, 2020 | 110 | 2020 |
| Metformin, phenformin, and galegine inhibit complex IV activity and reduce glycerol-derived gluconeogenesis TE LaMoia, GM Butrico, HA Kalpage, L Goedeke, BT Hubbard, DF Vatner, ... Proceedings of the National Academy of Sciences 119 (10), e2122287119, 2022 | 52 | 2022 |
| Regulation of Respiration and Apoptosis by Cytochrome c Threonine 58 Phosphorylation J Wan, HA Kalpage, A Vaishnav, J Liu, I Lee, G Mahapatra, AA Turner, ... Scientific reports 9 (1), 15815, 2019 | 49 | 2019 |
| Reanalysis of BRCA1/2 negative high risk ovarian cancer patients reveals novel germline risk loci and insights into missing heritability JL Stafford, G Dyson, NK Levin, S Chaudhry, R Rosati, H Kalpage, ... PLoS One 12 (6), e0178450, 2017 | 47 | 2017 |
| Cotargeting of mitochondrial complex I and Bcl-2 shows antileukemic activity against acute myeloid leukemia cells reliant on oxidative phosphorylation F Liu, HA Kalpage, D Wang, H Edwards, M Hüttemann, J Ma, Y Su, ... Cancers 12 (9), 2400, 2020 | 36 | 2020 |
| Targeting mitochondrial respiration for the treatment of acute myeloid leukemia JL Carter, K Hege, HA Kalpage, H Edwards, M Hüttemann, JW Taub, ... Biochemical pharmacology 182, 114253, 2020 | 34 | 2020 |
| Serine-47 phosphorylation of cytochrome c in the mammalian brain regulates cytochrome c oxidase and caspase-3 activity HA Kalpage, A Vaishnav, J Liu, A Varughese, J Wan, AA Turner, Q Ji, ... The FASEB Journal 33 (12), 13503, 2019 | 34 | 2019 |
| Cellular pharmacodynamics of a novel pyrrolo [3, 2-d] pyrimidine inhibitor targeting mitochondrial and cytosolic one-carbon metabolism AS Dekhne, C Ning, MJ Nayeen, K Shah, H Kalpage, J Frühauf, ... Molecular Pharmacology 97 (1), 9-22, 2020 | 30 | 2020 |
| Lysine 53 Acetylation of Cytochrome c in Prostate Cancer: Warburg Metabolism and Evasion of Apoptosis V Bazylianska, HA Kalpage, J Wan, A Vaishnav, G Mahapatra, AA Turner, ... Cells 10 (4), 802, 2021 | 18 | 2021 |
| Brain-Specific Serine-47 Modification of Cytochrome c Regulates Cytochrome c Oxidase Activity Attenuating ROS Production and Cell Death: Implications for … HA Kalpage, J Wan, PT Morse, I Lee, M Hüttemann Cells 9 (8), 1843, 2020 | 16 | 2020 |
| A Study on Hereditary Thrombophilia and Stroke in a Cohort from Sri Lanka HA Kalpage, DS Sumathipala, HW Goonasekara, VH Dissanayake Journal of Stroke and Cerebrovascular Diseases 25 (1), 102-109, 2016 | 11 | 2016 |
| Co-targeting of HDAC, PI3K, and Bcl-2 results in metabolic and transcriptional reprogramming and decreased mitochondrial function in acute myeloid leukemia KH Hurrish, X Qiao, X Li, Y Su, J Carter, J Ma, HA Kalpage, M Hüttemann, ... Biochemical pharmacology 205, 115283, 2022 | 10 | 2022 |
| Germline mutations in apoptosis pathway genes in ovarian cancer; the functional role of a TP53I3 (PIG3) variant in ROS production and DNA repair SR Chaudhry, J Lopes, NK Levin, H Kalpage, MA Tainsky Cell Death Discovery 7 (1), 62, 2021 | 9 | 2021 |
| Cytochrome c lysine acetylation regulates cellular respiration and cell death in ischemic skeletal muscle PT Morse, G Pérez-Mejías, J Wan, AA Turner, I Márquez, HA Kalpage, ... Nature Communications 14 (1), 4166, 2023 | 3 | 2023 |
| A novel isoflavone, ME-344, enhances venetoclax antileukemic activity against AML via suppression of oxidative phosphorylation and purine biosynthesis KH Hurrish, Y Su, S Wiley, Z Hou, J Carter, H Kalpage, M Hüttemann, ... Blood 138, 2238, 2021 | 1 | 2021 |
| Enhancing the antileukemic activity of venetoclax against leukemia stem cells by targeting oxidative phosphorylation through dual inhibition of PI3K and HDAC K Hege, H Kalpage, M Hüttemann, H Pitman, JW Taub, L Polin, J Li, Y Ge Cancer Research 81 (13_Supplement), 2463-2463, 2021 | 1 | 2021 |
| ME-344, a novel isoflavone mitochondrial inhibitor, in combination with venetoclax constitutes a new metabolism-targeted approach to overcome resistance to Bcl-2 inhibition and … KH Hurrish, Y Su, S Patel, SE Wiley, Z Hou, J Carter, H Kalpage, ... Cancer Research 82 (12_Supplement), 3785-3785, 2022 | | 2022 |
