| Identification of NVP-BKM120 as a potent, selective, orally bioavailable class I PI3 kinase inhibitor for treating cancer MT Burger, S Pecchi, A Wagman, ZJ Ni, M Knapp, T Hendrickson, ... ACS medicinal chemistry letters 2 (10), 774-779, 2011 | 267 | 2011 |
| Versatile approach to encoding combinatorial organic syntheses using chemically robust secondary amine tags ZJ Ni, D Maclean, CP Holmes, MM Murphy, B Ruhland, JW Jacobs, ... Journal of medicinal chemistry 39 (8), 1601-1608, 1996 | 177 | 1996 |
| CHIR-124, a Novel Potent Inhibitor of Chk1, Potentiates the Cytotoxicity of Topoisomerase I Poisons In vitro and In vivo AN Tse, KG Rendahl, T Sheikh, H Cheema, K Aardalen, M Embry, S Ma, ... Clinical Cancer Research 13 (2), 591-602, 2007 | 165 | 2007 |
| Anti‐HCV therapies in chimeric scid‐Alb/uPA mice parallel outcomes in human clinical application NM Kneteman, AJ Weiner, J O'Connell, M Collett, T Gao, L Aukerman, ... Hepatology 43 (6), 1346-1353, 2006 | 128 | 2006 |
| Encoded combinatorial chemistry: Synthesis and screening of a library of highly functionalized pyrrolidines D Maclean, JR Schullek, MM Murphy, ZJ Ni, EM Gordon, MA Gallop Proceedings of the National Academy of Sciences 94 (7), 2805-2810, 1997 | 113 | 1997 |
| The discovery of tetrahydro-β-carbolines as inhibitors of the kinesin Eg5 PA Barsanti, W Wang, ZJ Ni, D Duhl, N Brammeier, E Martin, D Bussiere, ... Bioorganic & medicinal chemistry letters 20 (1), 157-160, 2010 | 107 | 2010 |
| Transition-metal-mediated CS bond cleavage reactions TY Luh, ZJ Ni Synthesis 1990 (02), 89-103, 1990 | 102 | 1990 |
| (Phenylsulfonyl) allenes as Substrates for Cycloaddition Reactions: Intramolecular Cyclizations onto Unactivated Alkenes A Padwa, M Meske, SS Murphree, SH Watterson, Z Ni Journal of the American Chemical Society 117 (27), 7071-7080, 1995 | 95 | 1995 |
| Benzimidazole quinolinones and uses thereof PA Barsanti, D Bussiere, SD Harrison, CC Heise, JM Jansen, E Jazan, ... US Patent 7,470,709, 2008 | 94 | 2008 |
| Progress and development of small molecule HCV antivirals. ZJ Ni, AS Wagman Current Opinion in Drug Discovery & Development 7 (4), 446-459, 2004 | 88 | 2004 |
| 4-(Aminoalkylamino)-3-benzimidazole-quinolinones as potent CHK-1 inhibitors ZJ Ni, P Barsanti, N Brammeier, A Diebes, DJ Poon, S Ng, S Pecchi, ... Bioorganic & medicinal chemistry letters 16 (12), 3121-3124, 2006 | 79 | 2006 |
| Unified Synthesis of Vinylsilanes and Silylated Butadienes. Nickel-Catalyzed Olefination and Silyloefination of Dithioacetals ZJ Ni, PF Yang, DKP Ng, YL Tzeng, TY Luh Journal of the American Chemical Society 112, 1990 | 69 | 1990 |
| Synthesis of novel bicyclic nitrogen heterocycles by the intramolecular dipolar cycloaddition reaction of nitrones with allenes and alkynes A Padwa, M Meske, Z Ni Tetrahedron 51 (1), 89-106, 1995 | 64 | 1995 |
| Combination therapy with CHK1 inhibitors T Gesner, P Barsanti, S Harrison, ZJ Ni, N Brammeier, Y Zhou, V Le US Patent App. 11/041,191, 2005 | 62 | 2005 |
| Synthesis and SAR of acyclic HCV NS3 protease inhibitors with novel P4-benzoxaborole moieties X Li, S Zhang, YK Zhang, Y Liu, CZ Ding, Y Zhou, JJ Plattner, SJ Baker, ... Bioorganic & medicinal chemistry letters 21 (7), 2048-2054, 2011 | 61 | 2011 |
| Pyrimidine derivatives used as PI-3-kinase inhibitors M Burger, ZJ Ni, S Pecchi, G Atallah, S Bartulis, K Frazier, A Smith, ... US Patent 8,217,035, 2012 | 59 | 2012 |
| Synthesis and evaluation of novel α-amino cyclic boronates as inhibitors of HCV NS3 protease X Li, YK Zhang, Y Liu, CZ Ding, Q Li, Y Zhou, JJ Plattner, SJ Baker, X Qian, ... Bioorganic & medicinal chemistry letters 20 (12), 3550-3556, 2010 | 59 | 2010 |
| Synthesis and biological evaluations of P4-benzoxaborole-substituted macrocyclic inhibitors of HCV NS3 protease CZ Ding, YK Zhang, X Li, Y Liu, S Zhang, Y Zhou, JJ Plattner, SJ Baker, ... Bioorganic & medicinal chemistry letters 20 (24), 7317-7322, 2010 | 54 | 2010 |
| Cyclization reactions of 2, 3-bis (phenylsulfonyl)-1, 3-butadiene with various carbanions. A [4+ 1] anionic annulation approach to phenylsulfonyl-substituted cyclopentenes A Padwa, MA Filipkowski, M Meske, SS Murphree, SH Watterson, Z Ni The Journal of Organic Chemistry 59 (3), 588-596, 1994 | 49 | 1994 |
| Peri and stereoselectivity effects in the intramolecular [2+ 2]-cycloaddition reaction of phenylsulfonyl-substituted allenes A Padwa, MA Filipkowski, M Meske, SH Watterson, Z Ni Journal of the American Chemical Society 115 (9), 3776-3777, 1993 | 49 | 1993 |
