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Steffen Storck
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Endothelial LRP1 transports amyloid-β1–42 across the blood-brain barrier
SE Storck, S Meister, J Nahrath, JN Meißner, N Schubert, A Di Spiezio, ...
The Journal of clinical investigation 126 (1), 123-136, 2016
3792016
The concerted amyloid-beta clearance of LRP1 and ABCB1/P-gp across the blood-brain barrier is linked by PICALM
SE Storck, AMS Hartz, J Bernard, A Wolf, A Kachlmeier, A Mahringer, ...
Brain, behavior, and immunity 73, 21-33, 2018
1002018
Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid
A Drieu, S Du, SE Storck, J Rustenhoven, Z Papadopoulos, T Dykstra, ...
Nature 611 (7936), 585-593, 2022
962022
Enzyme replacement therapy with recombinant pro-CTSD (cathepsin D) corrects defective proteolysis and autophagy in neuronal ceroid lipofuscinosis
ARA Marques, A Di Spiezio, N Thießen, L Schmidt, J Grötzinger, ...
Autophagy 16 (5), 811-825, 2020
912020
LRP1 has a predominant role in production over clearance of Aβ in a mouse model of Alzheimer’s disease
B Van Gool, SE Storck, SM Reekmans, B Lechat, PLSM Gordts, L Pradier, ...
Molecular neurobiology 56, 7234-7245, 2019
882019
The LepR-mediated leptin transport across brain barriers controls food reward
A Di Spiezio, ES Sandin, R Dore, H Müller-Fielitz, SE Storck, M Bernau, ...
Molecular metabolism 8, 13-22, 2018
882018
Regulatory effects of simvastatin and apoJ on APP processing and amyloid-β clearance in blood-brain barrier endothelial cells
M Zandl-Lang, E Fanaee-Danesh, Y Sun, NM Albrecher, CC Gali, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2018
612018
Endothelial LRP1–a potential target for the treatment of Alzheimer’s disease: Theme: Drug discovery, development and delivery in Alzheimer’s disease Guest Editor: Davide Brambilla
SE Storck, CU Pietrzik
Pharmaceutical research 34 (12), 2637-2651, 2017
562017
The metalloprotease ADAMTS4 generates N-truncated Aβ4–x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer’s disease
S Walter, T Jumpertz, M Hüttenrauch, I Ogorek, H Gerber, SE Storck, ...
Acta neuropathologica 137, 239-257, 2019
542019
Low density lipoprotein receptor-related protein 1 mediated endocytosis of β1-integrin influences cell adhesion and cell migration
VK Rabiej, T Pflanzner, T Wagner, K Goetze, SE Storck, JA Eble, ...
Experimental cell research 340 (1), 102-115, 2016
432016
The blood-brain barrier in Alzheimer’s disease
SE Storck, AMS Hartz, CU Pietrzik
Physiology, pharmacology and pathology of the blood-brain barrier, 247-266, 2021
212021
Expression of the ALS-Causing Variant hSOD1G93A Leads to an Impaired Integrity and Altered Regulation of Claudin-5 Expression in an in Vitro Blood–Spinal …
S Meister, SE Storck, E Hameister, C Behl, S Weggen, AM Clement, ...
Journal of Cerebral Blood Flow & Metabolism 35 (7), 1112-1121, 2015
212015
PCSK9 acts as a key regulator of Aβ clearance across the blood–brain barrier
AD Mazura, A Ohler, SE Storck, M Kurtyka, F Scharfenberg, S Weggen, ...
Cellular and Molecular Life Sciences 79 (4), 212, 2022
202022
Brain endothelial LRP1 maintains blood–brain barrier integrity
SE Storck, M Kurtyka, CU Pietrzik
Fluids and Barriers of the CNS 18 (1), 27, 2021
202021
LRP1 modulates APP intraneuronal transport and processing in its monomeric and dimeric state
UM Herr, P Strecker, SE Storck, C Thomas, V Rabiej, A Junker, S Schilling, ...
Frontiers in molecular neuroscience 10, 118, 2017
162017
Age-related alterations in meningeal immunity drive impaired CNS lymphatic drainage
J Rustenhoven, G Pavlou, SE Storck, T Dykstra, S Du, Z Wan, D Quintero, ...
Journal of Experimental Medicine 220 (7), e20221929, 2023
142023
The Blood brain-barrier and its role in Alzheimer’s disease
SE Storck, CU Pietrzik
Neuroforum 24 (4), A197-A205, 2018
122018
Meprin β: A novel regulator of blood–brain barrier integrity
M Gindorf, SE Storck, A Ohler, F Scharfenberg, C Becker-Pauly, ...
Journal of Cerebral Blood Flow & Metabolism 41 (1), 31-44, 2021
102021
Meprin β knockout reduces brain Aβ levels and rescues learning and memory impairments in the APP/lon mouse model for Alzheimer’s disease
L Marengo, F Armbrust, C Schoenherr, SE Storck, U Schmitt, S Zampar, ...
Cellular and Molecular Life Sciences 79 (3), 168, 2022
92022
Identification of direct connections between the dura and the brain
LCD Smyth, D Xu, SV Okar, T Dykstra, J Rustenhoven, Z Papadopoulos, ...
Nature, 1-9, 2024
62024
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