IgG4 subclass antibodies impair antitumor immunity in melanoma P Karagiannis, AE Gilbert, DH Josephs, N Ali, T Dodev, L Saul, I Correa, ... The Journal of clinical investigation 123 (4), 1457-1474, 2013 | 224 | 2013 |
Efficient bifunctional gallium-68 chelators for positron emission tomography: tris (hydroxypyridinone) ligands DJ Berry, Y Ma, JR Ballinger, R Tavaré, A Koers, K Sunassee, T Zhou, ... Chemical communications 47 (25), 7068-7070, 2011 | 182 | 2011 |
FS118, a bispecific antibody targeting LAG-3 and PD-L1, enhances T-cell activation resulting in potent antitumor activity M Kraman, M Faroudi, NL Allen, K Kmiecik, D Gliddon, C Seal, A Koers, ... Clinical cancer research 26 (13), 3333-3344, 2020 | 96 | 2020 |
Monitoring the systemic human memory B cell compartment of melanoma patients for anti-tumor IgG antibodies AE Gilbert, P Karagiannis, T Dodev, A Koers, K Lacy, DH Josephs, ... PloS one 6 (4), e19330, 2011 | 91 | 2011 |
Rapid optical imaging of EGF receptor expression with a single-chain antibody SNAP-tag fusion protein F Kampmeier, J Niesen, A Koers, M Ribbert, A Brecht, R Fischer, ... European journal of nuclear medicine and molecular imaging 37, 1926-1934, 2010 | 75 | 2010 |
Anti-folate receptor-α IgE but not IgG recruits macrophages to attack tumors via TNFα/MCP-1 signaling DH Josephs, HJ Bax, T Dodev, M Georgouli, M Nakamura, G Pellizzari, ... Cancer research 77 (5), 1127-1141, 2017 | 73 | 2017 |
In vivo SPECT reporter gene imaging of regulatory T cells E Sharif-Paghaleh, K Sunassee, R Tavaré, K Ratnasothy, A Koers, N Ali, ... PloS one 6 (10), e25857, 2011 | 65 | 2011 |
Recombinant IgE antibodies for passive immunotherapy of solid tumours: from concept towards clinical application SN Karagiannis, DH Josephs, P Karagiannis, AE Gilbert, L Saul, ... Cancer Immunology, Immunotherapy 61, 1547-1564, 2012 | 59 | 2012 |
Harnessing engineered antibodies of the IgE class to combat malignancy: initial assessment of FcɛRI‐mediated basophil activation by a tumour‐specific IgE antibody to evaluate … SM Rudman, DH Josephs, H Cambrook, P Karagiannis, AE Gilbert, ... Clinical & Experimental Allergy 41 (10), 1400-1413, 2011 | 48 | 2011 |
FS222, a CD137/PD-L1 tetravalent bispecific antibody, exhibits low toxicity and antitumor activity in colorectal cancer models MA Lakins, A Koers, R Giambalvo, J Munoz-Olaya, R Hughes, ... Clinical Cancer Research 26 (15), 4154-4167, 2020 | 46 | 2020 |
p53 loss in MYC-driven neuroblastoma leads to metabolic adaptations supporting radioresistance O Yogev, K Barker, A Sikka, GS Almeida, A Hallsworth, LM Smith, Y Jamin, ... Cancer research 76 (10), 3025-3035, 2016 | 36 | 2016 |
SHH pathway inhibition is protumourigenic in adamantinomatous craniopharyngioma G Carreno, JKR Boult, J Apps, JM Gonzalez-Meljem, S Haston, R Guiho, ... Endocrine-related cancer 26 (3), 355-366, 2019 | 26 | 2019 |
MRI imaging of the hemodynamic vasculature of neuroblastoma predicts response to antiangiogenic treatment K Zormpas-Petridis, NP Jerome, MD Blackledge, F Carceller, E Poon, ... Cancer research 79 (11), 2978-2991, 2019 | 22 | 2019 |
Noninvasive MRI Native T1 Mapping Detects Response to MYCN-targeted Therapies in the Th-MYCN Model of Neuroblastoma K Zormpas-Petridis, E Poon, M Clarke, NP Jerome, JKR Boult, ... Cancer research 80 (16), 3424-3435, 2020 | 21 | 2020 |
Preclinical transgenic and patient‐derived xenograft models recapitulate the radiological features of human adamantinomatous craniopharyngioma JKR Boult, JR Apps, A Hölsken, JC Hutchinson, G Carreno, LS Danielson, ... Brain pathology 28 (4), 475-483, 2018 | 19 | 2018 |
Dual blockade of PD-L1 and LAG-3 with FS118, a unique bispecific antibody, induces CD8+ T-cell activation and modulates the tumor microenvironment to promote antitumor immune … M Kraman, N Fosh, K Kmiecik, K Everett, C Zimarino, M Faroudi, M Wydro, ... Cancer research 78 (13_Supplement), 2719-2719, 2018 | 16 | 2018 |
Anti-cancer pro-inflammatory effects of an IgE antibody targeting the melanoma-associated antigen chondroitin sulfate proteoglycan 4 J Chauhan, M Grandits, LCGF Palhares, S Mele, M Nakamura, ... Nature Communications 14 (1), 2192, 2023 | 8 | 2023 |
Dual blockade of PD-L1 and LAG-3 with FS118, a unique bispecific antibody, induces T-cell activation with the potential to drive potent anti-tumour immune responses M Kraman, N Fosh, K Kmiecik, K Everett, C Zimarino, M Faroudi, M Wydro, ... J. Immunother. Cancer 5, P348, 2017 | 6 | 2017 |
Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRASG12C with Demonstrable CNS Penetration JG Kettle, SK Bagal, D Barratt, MS Bodnarchuk, S Boyd, E Braybrooke, ... Journal of Medicinal Chemistry 66 (13), 9147-9160, 2023 | 3 | 2023 |
Metal ion chelation as a basis for pretargeting PJ Blower, MS Cooper, S Nawaz, A O'Neill, A Koers, K Sunassee, ... EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 39, S262-S262, 2012 | 3 | 2012 |