| Whole-genome sequencing analysis of phenotypic heterogeneity and anticipation in Li–Fraumeni cancer predisposition syndrome H Ariffin, P Hainaut, A Puzio-Kuter, SS Choong, ASL Chan, D Tolkunov, ... Proceedings of the National Academy of Sciences 111 (43), 15497-15501, 2014 | 42 | 2014 |
| Reliable genotyping of the koala (Phascolarctos cinereus) using DNA isolated from a single faecal pellet F Wedrowicz, M Karsa, J Mosse, FE Hogan Molecular ecology resources 13 (4), 634-641, 2013 | 36 | 2013 |
| Potent antileukemic activity of curaxin CBL0137 against MLL‐rearranged leukemia K Somers, A Kosciolek, A Bongers, A El‐Ayoubi, M Karsa, C Mayoh, ... International Journal of Cancer 146 (7), 1902-1916, 2020 | 31 | 2020 |
| Improving the identification of high risk precursor B acute lymphoblastic leukemia patients with earlier quantification of minimal residual disease M Karsa, L Dalla Pozza, NC Venn, T Law, R Shi, JE Giles, AY Bahar, ... PloS one 8 (10), e76455, 2013 | 26 | 2013 |
| Effective targeting of NAMPT in patient-derived xenograft models of high-risk pediatric acute lymphoblastic leukemia K Somers, K Evans, L Cheung, M Karsa, T Pritchard, A Kosciolek, ... Leukemia 34 (6), 1524-1539, 2020 | 24 | 2020 |
| A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction K Somers, VW Wen, S Middlemiss, B Osborne, H Forgham, MS Jung, ... Oncogene 38 (20), 3824-3842, 2019 | 22 | 2019 |
| Exploiting the reactive oxygen species imbalance in high-risk paediatric acute lymphoblastic leukaemia through auranofin M Karsa, A Kosciolek, A Bongers, A Mariana, T Failes, AJ Gifford, ... British journal of cancer 125 (1), 55-64, 2021 | 19 | 2021 |
| Frequent occurrence of gastric cancer in Asian kindreds with Li–Fraumeni syndrome H Ariffin, ASL Chan, L Oh, S Abd‐Ghafar, GB Ong, M Mohamed, H Razali, ... Clinical genetics 88 (5), 450-455, 2015 | 18 | 2015 |
| Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in NeuroblastomaDual … L Xiao, K Somers, J Murray, R Pandher, M Karsa, E Ronca, A Bongers, ... Clinical Cancer Research 27 (15), 4338-4352, 2021 | 17 | 2021 |
| CCI-007, a novel small molecule with cytotoxic activity against infant leukemia with MLL rearrangements K Somers, DA Chudakova, SMC Middlemiss, VW Wen, M Clifton, A Kwek, ... Oncotarget 7 (29), 46067, 2016 | 14 | 2016 |
| The Combination of Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Delays KMT2A-Rearranged Leukemia Progression L Xiao, M Karsa, E Ronca, A Bongers, A Kosciolek, A El-Ayoubi, ... Frontiers in oncology 12, 863329, 2022 | 9 | 2022 |
| Direct targeted therapy for MLL‐fusion‐driven high‐risk acute leukaemias S Cantilena, L Gasparoli, D Pal, O Heidenreich, JH Klusmann, ... Clinical and translational medicine 12 (6), e933, 2022 | 8 | 2022 |
| Systematic In Vitro Evaluation of a Library of Approved and Pharmacologically Active Compounds for the Identification of Novel Candidate Drugs for KMT2A … M Karsa, E Ronca, A Bongers, A Mariana, E Moles, TW Failes, GM Arndt, ... Frontiers in oncology 11, 779859-779859, 2021 | 3 | 2021 |
| CBL0137 promotes CART-cell therapy against MLL-rearranged leukemia M Karsa, N Xu, T Tang, M Haber, K Somers, A Dolnikov ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY 17, 11-12, 2021 | | 2021 |
| Targeting chromatin potently inhibits leukemia progression in MLL-rearranged leukemia models L Xiao, M Karsa, E Ronca, A Bongers, W Gao, A Kosciolek, A El-Ayoubi, ... ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY 17, 15-15, 2021 | | 2021 |
| PO-405 Repositioning existing drugs as novel therapeutics for high-risk paediatric leukaemia M Karsa, T Failes, GM Arndt, UR Kees, M Haber, MD Norris, R Sutton, ... ESMO Open 3, A181, 2018 | | 2018 |
| Novel therapies for high-risk leukaemia in children M Karsa UNSW Sydney, 2018 | | 2018 |
| The nicotinamide phosphoribosyltransferase (NAMPT) inhibitor, OT-82, exhibits in vitro and in vivo efficacy against patient-derived xenograft models of high-risk … K Evans, T Pritchard, MJ Henderson, K Somers, M Karsa, L Cheung, ... Cancer Research 77 (13_Supplement), 1942-1942, 2017 | | 2017 |
| Inhibition of NAMPT as a novel therapeutic strategy for infant leukemia K Somers, S Middlemiss, A Biktasova, M Karsa, L Cheung, A Kosciolek, ... Cancer Research 77 (13_Supplement), 1175-1175, 2017 | | 2017 |
| REPOSITIONING EXISTING DRUGS AS NOVEL THERAPEUTICS: OXIDATIVE STRESS AS A TARGET FOR HIGH-RISK LEUKAEMIA IN CHILDREN M Karsa, K Somers, A Mariana, T Failes, GM Arndt, UR Kees, M Haber, ... HAEMATOLOGICA 102, 27-27, 2017 | | 2017 |
