MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia SA Armstrong, JE Staunton, LB Silverman, R Pieters, ML den Boer, ... Nature genetics 30 (1), 41-47, 2002 | 2560 | 2002 |
A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study ML Den Boer, M van Slegtenhorst, RX De Menezes, MH Cheok, ... The lancet oncology 10 (2), 125-134, 2009 | 1095 | 2009 |
Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment A Holleman, MH Cheok, ML den Boer, W Yang, AJP Veerman, ... New England Journal of Medicine 351 (6), 533-542, 2004 | 726 | 2004 |
Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance G Wei, D Twomey, J Lamb, K Schlis, J Agarwal, RW Stam, JT Opferman, ... Cancer cell 10 (4), 331-342, 2006 | 576 | 2006 |
Inhibition of FLT3 in MLL: validation of a therapeutic target identified by gene expression based classification SA Armstrong, AL Kung, ME Mabon, LB Silverman, RW Stam, ... Cancer cell 3 (2), 173-183, 2003 | 509 | 2003 |
Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL A Van der Veer, E Waanders, R Pieters, ME Willemse, ... Blood, The Journal of the American Society of Hematology 122 (15), 2622-2629, 2013 | 321 | 2013 |
Relation between age, immunophenotype and in vitro drug resistance in 395 children with acute lymphoblastic leukemia–implications for treatment of infants R Pieters, ML Den Boer, M Durian, G Janka, K Schmiegelow, ... Leukemia 12 (9), 1344-1348, 1998 | 303 | 1998 |
The MLL recombinome of acute leukemias C Meyer, B Schneider, S Jakob, S Strehl, A Attarbaschi, S Schnittger, ... Leukemia 20 (5), 777-784, 2006 | 281 | 2006 |
Inhibition of glycolysis modulates prednisolone resistance in acute lymphoblastic leukemia cells E Hulleman, KM Kazemier, A Holleman, DJ VanderWeele, CM Rudin, ... Blood, The Journal of the American Society of Hematology 113 (9), 2014-2021, 2009 | 257 | 2009 |
Differential mRNA expression of Ara-C–metabolizing enzymes explains Ara-C sensitivity in MLL gene–rearranged infant acute lymphoblastic leukemia RW Stam, ML den Boer, JPP Meijerink, MEG Ebus, GJ Peters, ... Blood, The Journal of the American Society of Hematology 101 (4), 1270-1276, 2003 | 244 | 2003 |
MicroRNA characterize genetic diversity and drug resistance in pediatric acute lymphoblastic leukemia D Schotte, RX De Menezes, FA Moqadam, LM Khankahdani, ... haematologica 96 (5), 703, 2011 | 239 | 2011 |
Identification of new microRNA genes and aberrant microRNA profiles in childhood acute lymphoblastic leukemia D Schotte, JCK Chau, G Sylvester, G Liu, C Chen, VHJ Van Der Velden, ... Leukemia 23 (2), 313-322, 2009 | 238 | 2009 |
Patient stratification based on prednisolone-vincristine-asparaginase resistance profiles in children with acute lymphoblastic leukemia ML Den Boer, DO Harms, R Pieters, KM Kazemier, U Gobel, D Korholz, ... Journal of clinical oncology 21 (17), 3262-3268, 2003 | 212 | 2003 |
Sensitivity to l-asparaginase is not associated with expression levels of asparagine synthetase in t(12;21)+pediatric ALL WAG Stams, ML den Boer, HB Beverloo, JPP Meijerink, RL Stigter, ... Blood, The Journal of the American Society of Hematology 101 (7), 2743-2747, 2003 | 210 | 2003 |
Molecular determinants of glucocorticoid sensitivity and resistance in acute lymphoblastic leukemia WJE Tissing, JPP Meijerink, ML den Boer, R Pieters Leukemia 17 (1), 17-25, 2003 | 210 | 2003 |
Targeting FLT3 in primary MLL-gene–rearranged infant acute lymphoblastic leukemia RW Stam, ML den Boer, P Schneider, P Nollau, M Horstmann, ... Blood 106 (7), 2484-2490, 2005 | 202 | 2005 |
Tunneling nanotubes and gap junctions–their role in long-range intercellular communication during development, health, and disease conditions J Ariazi, A Benowitz, V De Biasi, ML Den Boer, S Cherqui, H Cui, ... Frontiers in molecular neuroscience 10, 333, 2017 | 200 | 2017 |
Prognostic significance of minimal residual disease in infants with acute lymphoblastic leukemia treated within the Interfant-99 protocol VHJ Van der Velden, L Corral, MG Valsecchi, M Jansen, P De Lorenzo, ... Leukemia 23 (6), 1073-1079, 2009 | 198 | 2009 |
The expression of 70 apoptosis genes in relation to lineage, genetic subtype, cellular drug resistance, and outcome in childhood acute lymphoblastic leukemia A Holleman, ML den Boer, RX de Menezes, MH Cheok, C Cheng, ... Blood 107 (2), 769-776, 2006 | 198 | 2006 |
Identification of genes associated with chemotherapy crossresistance and treatment response in childhood acute lymphoblastic leukemia S Lugthart, MH Cheok, ML den Boer, W Yang, A Holleman, C Cheng, ... Cancer cell 7 (4), 375-386, 2005 | 194 | 2005 |