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Alison Ringel
Alison Ringel
Assistant Professor, MIT Department of Biology; Core Member, Ragon Institute
Verified email at mit.edu
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Cited by
Year
Obesity shapes metabolism in the tumor microenvironment to suppress anti-tumor immunity
AE Ringel, JM Drijvers, GJ Baker, A Catozzi, JC García-Cañaveras, ...
Cell 183 (7), 1848-1866. e26, 2020
3952020
Metabolic recycling of ammonia via glutamate dehydrogenase supports breast cancer biomass
JB Spinelli, H Yoon, AE Ringel, S Jeanfavre, CB Clish, MC Haigis
Science 358 (6365), 941-946, 2017
3592017
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
AA Chakraborty, T Laukka, M Myllykoski, AE Ringel, MA Booker, ...
Science 363 (6432), 1217-1222, 2019
3462019
Mitochondrial sirtuin network reveals dynamic SIRT3-dependent deacetylation in response to membrane depolarization
W Yang, K Nagasawa, C Münch, Y Xu, K Satterstrom, S Jeong, SD Hayes, ...
Cell 167 (4), 985-1000. e21, 2016
2832016
Structural basis for histone H2B deubiquitination by the SAGA DUB module
MT Morgan, M Haj-Yahya, AE Ringel, P Bandi, A Brik, C Wolberger
Science 351 (6274), 725-728, 2016
2442016
Oncometabolite d-2HG alters T cell metabolism to impair CD8+ T cell function
G Notarangelo, JB Spinelli, EM Perez, GJ Baker, K Kurmi, I Elia, ...
Science 377 (6614), 1519-1529, 2022
1002022
A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation
H Zhao, R Ghirlando, C Alfonso, F Arisaka, I Attali, DL Bain, MM Bakhtina, ...
PloS one 10 (5), e0126420, 2015
952015
Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8+ T Cells
JM Drijvers, JE Gillis, T Muijlwijk, TH Nguyen, EF Gaudiano, IS Harris, ...
Cancer immunology research 9 (2), 184-199, 2021
922021
The bromodomain of Gcn5 regulates site specificity of lysine acetylation on histone H3
AM Cieniewicz, L Moreland, AE Ringel, SG Mackintosh, A Raman, ...
Molecular & Cellular Proteomics 13 (11), 2896-2910, 2014
872014
A conserved asparagine has a structural role in ubiquitin-conjugating enzymes
CE Berndsen, R Wiener, IW Yu, AE Ringel, C Wolberger
Nature chemical biology 9 (3), 154-156, 2013
752013
Adaptation of human iPSC-derived cardiomyocytes to tyrosine kinase inhibitors reduces acute cardiotoxicity via metabolic reprogramming
H Wang, RP Sheehan, AC Palmer, RA Everley, SA Boswell, N Ron-Harel, ...
Cell systems 8 (5), 412-426. e7, 2019
592019
Yeast Tdh3 (glyceraldehyde 3-phosphate dehydrogenase) is a Sir2-interacting factor that regulates transcriptional silencing and rDNA recombination
AE Ringel, R Ryznar, H Picariello, K Huang, AG Lazarus, SG Holmes
PLOS genetics 9 (10), e1003871, 2013
592013
Structural basis for acyl-group discrimination by human Gcn5L2
AE Ringel, C Wolberger
Acta Crystallographica Section D: Structural Biology 72 (7), 841-848, 2016
572016
Nucleosome competition reveals processive acetylation by the SAGA HAT module
AE Ringel, AM Cieniewicz, SD Taverna, C Wolberger
Proceedings of the National Academy of Sciences 112 (40), E5461-E5470, 2015
542015
Chemical and physiological features of mitochondrial acylation
AE Ringel, SA Tucker, MC Haigis
Molecular cell 72 (4), 610-624, 2018
392018
Small-molecule screen identifies de novo nucleotide synthesis as a vulnerability of cells lacking SIRT3
KNG Herrera, E Zaganjor, Y Ishikawa, JB Spinelli, H Yoon, JR Lin, ...
Cell reports 22 (8), 1945-1955, 2018
342018
Characterization of the SUMO-binding activity of the myeloproliferative and mental retardation (MYM)-type zinc fingers in ZNF261 and ZNF198
CM Guzzo, A Ringel, E Cox, I Uzoma, H Zhu, S Blackshaw, C Wolberger, ...
PloS one 9 (8), e105271, 2014
332014
A role for intersubunit interactions in maintaining SAGA deubiquitinating module structure and activity
NL Samara, AE Ringel, C Wolberger
Structure 20 (8), 1414-1424, 2012
332012
Astrocyte deletion of α2-Na/K ATPase triggers episodic motor paralysis in mice via a metabolic pathway
SE Smith, X Chen, LM Brier, JR Bumstead, NR Rensing, AE Ringel, ...
Nature communications 11 (1), 6164, 2020
272020
Age-associated remodeling of T cell immunity and metabolism
SJ Han, P Georgiev, AE Ringel, AH Sharpe, MC Haigis
Cell metabolism 35 (1), 36-55, 2023
212023
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Articles 1–20