| Binding of ATP to heat shock protein 90: evidence for an ATP-binding site in the C-terminal domain C Garnier, D Lafitte, PO Tsvetkov, P Barbier, J Leclerc-Devin, JM Millot, ... Journal of Biological Chemistry 277 (14), 12208-12214, 2002 | 202 | 2002 |
| Synthesis and biological evaluation of 4-arylcoumarin analogues of combretastatins C Bailly, C Bal, P Barbier, S Combes, JP Finet, MP Hildebrand, V Peyrot, ... Journal of medicinal chemistry 46 (25), 5437-5444, 2003 | 179 | 2003 |
| Caulerpenyne from Caulerpa taxifolia has an antiproliferative activity on tumor cell line SK-N-SH and modifies the microtubule network P Barbier, S Guise, P Huitorel, P Amade, D Pesando, C Briand, V Peyrot Life Sciences 70 (4), 415-429, 2001 | 156 | 2001 |
| The glutamine-rich region of the HIV-1 Tat protein is involved in T-cell apoptosis GR Campbell, E Pasquier, J Watkins, V Bourgarel-Rey, V Peyrot, ... Journal of Biological Chemistry 279 (46), 48197-48204, 2004 | 150 | 2004 |
| New insights into the antibacterial mechanism of action of squalamine K Alhanout, S Malesinki, N Vidal, V Peyrot, JM Rolain, JM Brunel Journal of Antimicrobial Chemotherapy 65 (8), 1688-1693, 2010 | 124 | 2010 |
| NMR investigation of the interaction between the neuronal protein tau and the microtubules A Sillen, P Barbier, I Landrieu, S Lefebvre, JM Wieruszeski, A Leroy, ... Biochemistry 46 (11), 3055-3064, 2007 | 123 | 2007 |
| Stathmin and interfacial microtubule inhibitors recognize a naturally curved conformation of tubulin dimers P Barbier, A Dorléans, F Devred, L Sanz, D Allegro, C Alfonso, ... Journal of Biological Chemistry 285 (41), 31672-31681, 2010 | 114 | 2010 |
| Synthesis and biological evaluation of 4-arylcoumarin analogues of combretastatins. Part 2 S Combes, P Barbier, S Douillard, A McLeer-Florin, V Bourgarel-Rey, ... Journal of medicinal chemistry 54 (9), 3153-3162, 2011 | 112 | 2011 |
| Alzheimer disease specific phosphoepitopes of Tau interfere with assembly of tubulin but not binding to microtubules L Amniai, P Barbier, A Sillen, JM Wieruszeski, V Peyrot, G Lippens, ... The FASEB Journal 23 (4), 1146-1152, 2009 | 109 | 2009 |
| Heat-Shock Protein 90 (hsp90) Bindsin Vitroto Tubulin Dimer and Inhibits Microtubule Formation C Garnier, P Barbier, R Gilli, C Lopez, V Peyrot, C Briand Biochemical and biophysical research communications 250 (2), 414-419, 1998 | 107 | 1998 |
| A novel chalcone derivative which acts as a microtubule depolymerising agent and an inhibitor of P-gp and BCRP in in-vitro and in-vivoglioblastoma models A Boumendjel, A McLeer-Florin, P Champelovier, D Allegro, ... BMC cancer 9, 1-11, 2009 | 103 | 2009 |
| Interaction of 4-arylcoumarin analogues of combretastatins with microtubule network of HBL100 cells and binding to tubulin C Rappl, P Barbier, V Bourgarel-Rey, C Grégoire, R Gilli, M Carre, ... Biochemistry 45 (30), 9210-9218, 2006 | 99 | 2006 |
| Solution structure of Taxotere-induced microtubules to 3-nm resolution. The change in protofilament number is linked to the binding of the taxol side chain. JM Andreu, JF Díaz, R Gil, JM De Pereda, MG de Lacoba, V Peyrot, ... Journal of Biological Chemistry 269 (50), 31785-31792, 1994 | 96 | 1994 |
| Synthesis and biological evaluation of polymethoxylated 4-heteroarylcoumarins as tubulin assembly inhibitor OG Ganina, E Daras, V Bourgarel-Rey, V Peyrot, AN Andresyuk, JP Finet, ... Bioorganic & medicinal chemistry 16 (19), 8806-8812, 2008 | 92 | 2008 |
| Inhibition of microtubules and cell cycle arrest by a new 1-deaza-7, 8-dihydropteridine antitumor drug, CI 980, and by its chiral isomer, NSC 613863 C de Ines, D Leynadier, I Barasoain, V Peyrot, P Garcia, C Briand, ... Cancer research 54 (1), 75-84, 1994 | 84 | 1994 |
| HIV-1 Tat protein enhances microtubule polymerization J de Mareuil, M Carre, P Barbier, GR Campbell, S Lancelot, S Opi, ... Retrovirology 2, 1-11, 2005 | 81 | 2005 |
| Apo‐Hsp90 coexists in two open conformational states in solution P Bron, E Giudice, JP Rolland, RM Buey, P Barbier, JF Díaz, V Peyrot, ... Biology of the Cell 100 (7), 413-425, 2008 | 77 | 2008 |
| Mechanism of binding of the new antimitotic drug MDL 27048 to the colchicine site of tubulin: equilibrium studies V Peyrot, D Leynadier, M Sarrazin, C Briand, M Menendez, J Laynez, ... Biochemistry 31 (45), 11125-11132, 1992 | 70 | 1992 |
| Discovery of a new family of bis-8-hydroxyquinoline substituted benzylamines with pro-apoptotic activity in cancer cells: Synthesis, structure–activity relationship, and action … V Moret, Y Laras, T Cresteil, G Aubert, DQ Ping, C Di, ... European journal of medicinal chemistry 44 (2), 558-567, 2009 | 69 | 2009 |
| Tau induces ring and microtubule formation from αβ-tubulin dimers under nonassembly conditions F Devred, P Barbier, S Douillard, O Monasterio, JM Andreu, V Peyrot Biochemistry 43 (32), 10520-10531, 2004 | 67 | 2004 |
