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Jayakrishnan Nandakumar
Jayakrishnan Nandakumar
Associate Professor, University of Michigan
Bestätigte E-Mail-Adresse bei umich.edu - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Finding the end: recruitment of telomerase to telomeres
J Nandakumar, TR Cech
Nature reviews Molecular cell biology 14 (2), 69-82, 2013
4312013
The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity
J Nandakumar, CF Bell, I Weidenfeld, AJ Zaug, LA Leinwand, TR Cech
Nature 492 (7428), 285-289, 2012
3872012
Functional interaction between telomere protein TPP1 and telomerase
AJ Zaug, ER Podell, J Nandakumar, TR Cech
Genes & development 24 (6), 613-622, 2010
1672010
Structural biology of telomeres and telomerase
EM Smith, DF Pendlebury, J Nandakumar
Cellular and Molecular Life Sciences 77, 61-79, 2020
1572020
Hoyeraal-Hreidarsson syndrome caused by a germline mutation in the TEL patch of the telomere protein TPP1
H Kocak, BJ Ballew, K Bisht, R Eggebeen, BD Hicks, S Suman, A O’Neil, ...
Genes & development 28 (19), 2090-2102, 2014
1412014
RNA substrate specificity and structure-guided mutational analysis of bacteriophage T4 RNA ligase 2
J Nandakumar, CK Ho, CD Lima, S Shuman
Journal of Biological Chemistry 279 (30), 31337-31347, 2004
1102004
Last stop on the road to repair: structure of E. coli DNA ligase bound to nicked DNA-adenylate
J Nandakumar, PA Nair, S Shuman
Molecular cell 26 (2), 257-271, 2007
1062007
RNA ligase structures reveal the basis for RNA specificity and conformational changes that drive ligation forward
J Nandakumar, S Shuman, CD Lima
Cell 127 (1), 71-84, 2006
992006
How an RNA ligase discriminates RNA versus DNA damage
J Nandakumar, S Shuman
Molecular cell 16 (2), 211-221, 2004
952004
Structural basis for nick recognition by a minimal pluripotent DNA ligase
PA Nair, J Nandakumar, P Smith, M Odell, CD Lima, S Shuman
Nature structural & molecular biology 14 (8), 770-778, 2007
932007
RNA repair: an antidote to cytotoxic eukaryal RNA damage
J Nandakumar, B Schwer, R Schaffrath, S Shuman
Molecular cell 31 (2), 278-286, 2008
912008
Molecular mechanisms of telomere biology disorders
S Grill, J Nandakumar
Journal of Biological Chemistry 296, 2021
782021
How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA
J Nandakumar, ER Podell, TR Cech
Proceedings of the National Academy of Sciences 107 (2), 651-656, 2010
772010
Atomic structure and nonhomologous end-joining function of the polymerase component of bacterial DNA ligase D
H Zhu, J Nandakumar, J Aniukwu, LK Wang, MS Glickman, CD Lima, ...
Proceedings of the National Academy of Sciences 103 (6), 1711-1716, 2006
742006
Pot1 OB-fold mutations unleash telomere instability to initiate tumorigenesis
P Gu, Y Wang, KK Bisht, L Wu, L Kukova, EM Smith, Y Xiao, SM Bailey, ...
Oncogene 36 (14), 1939-1951, 2017
592017
Inhibition of telomerase recruitment and cancer cell death
M Nakashima, J Nandakumar, KD Sullivan, JM Espinosa, TR Cech
Journal of Biological Chemistry 288 (46), 33171-33180, 2013
582013
The shelterin complex and hematopoiesis
M Jones, K Bisht, SA Savage, J Nandakumar, CE Keegan, I Maillard
The Journal of clinical investigation 126 (5), 1621-1629, 2016
522016
The N terminus of the OB domain of telomere protein TPP1 is critical for telomerase action
S Grill, VM Tesmer, J Nandakumar
Cell reports 22 (5), 1132-1140, 2018
502018
The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells
J Zhang, M Gurusaran, Y Fujiwara, K Zhang, M Echbarthi, E Vorontsov, ...
Nature communications 11 (1), 2055, 2020
482020
Structural and functional consequences of a disease mutation in the telomere protein TPP1
K Bisht, EM Smith, VM Tesmer, J Nandakumar
Proceedings of the National Academy of Sciences 113 (46), 13021-13026, 2016
442016
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