| A high-throughput phenotypic screen identifies clofazimine as a potential treatment for cryptosporidiosis MS Love, FC Beasley, RS Jumani, TM Wright, AK Chatterjee, CD Huston, ... PLoS neglected tropical diseases 11 (2), e0005373, 2017 | 116 | 2017 |
| Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis B Baragaña, B Forte, R Choi, S Nakazawa Hewitt, JA Bueren-Calabuig, ... Proceedings of the National Academy of Sciences 116 (14), 7015-7020, 2019 | 105 | 2019 |
| Identification of Cryptosporidium parvum active chemical series by Repurposing the open access malaria box K Bessoff, T Spangenberg, JE Foderaro, RS Jumani, GE Ward, ... Antimicrobial agents and chemotherapy 58 (5), 2731-2739, 2014 | 95 | 2014 |
| Targeting prolyl-tRNA synthetase to accelerate drug discovery against malaria, leishmaniasis, toxoplasmosis, cryptosporidiosis, and coccidiosis V Jain, M Yogavel, H Kikuchi, Y Oshima, N Hariguchi, M Matsumoto, ... Structure 25 (10), 1495-1505. e6, 2017 | 75 | 2017 |
| Identification of a potent benzoxaborole drug candidate for treating cryptosporidiosis CS Lunde, EE Stebbins, RS Jumani, MM Hasan, P Miller, J Barlow, ... Nature communications 10 (1), 2816, 2019 | 57 | 2019 |
| A novel piperazine-based drug lead for cryptosporidiosis from the medicines for malaria venture open-access malaria box RS Jumani, K Bessoff, MS Love, P Miller, EE Stebbins, JE Teixeira, ... Antimicrobial Agents and Chemotherapy 62 (4), 10.1128/aac. 01505-17, 2018 | 53 | 2018 |
| Bicyclic azetidines kill the diarrheal pathogen Cryptosporidium in mice by inhibiting parasite phenylalanyl-tRNA synthetase S Vinayak, RS Jumani, P Miller, MM Hasan, BI McLeod, J Tandel, ... Science Translational Medicine 12 (563), eaba8412, 2020 | 48 | 2020 |
| Optimization of Methionyl tRNA-Synthetase Inhibitors for Treatment of Cryptosporidium Infection FS Buckner, RM Ranade, JR Gillespie, S Shibata, MA Hulverson, Z Zhang, ... Antimicrobial Agents and Chemotherapy 63 (4), 10.1128/aac. 02061-18, 2019 | 41 | 2019 |
| A suite of phenotypic assays to ensure pipeline diversity when prioritizing drug-like Cryptosporidium growth inhibitors RS Jumani, MM Hasan, EE Stebbins, L Donnelly, P Miller, C Klopfer, ... Nature communications 10 (1), 1862, 2019 | 33 | 2019 |
| Clinical and microbiologic efficacy of the piperazine-based drug lead MMV665917 in the dairy calf cryptosporidiosis model E Stebbins, RS Jumani, C Klopfer, J Barlow, P Miller, MA Campbell, ... PLoS neglected tropical diseases 12 (1), e0006183, 2018 | 33 | 2018 |
| The Glycosylated Rv1860 Protein of Mycobacterium tuberculosis Inhibits Dendritic Cell Mediated TH1 and TH17 Polarization of T Cells and Abrogates Protective … V Satchidanandam, N Kumar, RS Jumani, V Challu, S Elangovan, ... PLoS Pathogens 10 (6), e1004176, 2014 | 30 | 2014 |
| Discovery and structure activity relationship of the first potent cryptosporidium FIKK kinase inhibitor KT Osman, J Ye, Z Shi, C Toker, D Lovato, RS Jumani, W Zuercher, ... Bioorganic & medicinal chemistry 25 (5), 1672-1680, 2017 | 14 | 2017 |
| The Secreted Protein Rv1860 of Mycobacterium tuberculosis Stimulates Human Polyfunctional CD8+ T Cells V Satchidanandam, N Kumar, S Biswas, RS Jumani, C Jain, R Rani, ... Clinical and Vaccine Immunology 23 (4), 282-293, 2016 | 13 | 2016 |
| Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections SPS Rao, MK Gould, J Noeske, M Saldivia, RS Jumani, PS Ng, O René, ... Science 380 (6652), 1349-1356, 2023 | 9 | 2023 |
| Opportunities and Challenges in Developing a Cryptosporidium Controlled Human Infection Model for Testing Antiparasitic Agents RS Jumani, J Blais, HC Tillmann, F Segal, D Wetty, C Ostermeier, ... ACS Infectious Diseases 7 (5), 959-968, 2021 | 7 | 2021 |
| Rv3881c from Mycobacterium tuberculosis Elicits Poly-Functional CD8+ T cells in PPD-Positive Healthy Volunteers and Affords Significant Protection in the Guinea Pig Model V Satchidanandam, N Kumar, S Biswas, RS Jumani, C Jain J Immunol Tech Infect Dis 5 2, 2, 2016 | 3 | 2016 |
| Innovations in addressing pediatric diarrhea in low resource settings RS Jumani, JM Spector, R Izadnegahdar, P Kelly, TT Diagana, ... ACS infectious diseases 6 (1), 14-24, 2019 | 2 | 2019 |
| Cryptosporidium Life Cycle Small Molecule Probing Implicates Translational Repression And An Apetala 2 Transcription Factor In Sexual Differentiation MM Hasan, EB Mattice, JE Teixeira, RS Jumani, EE Stebbins, CE Klopfer, ... bioRxiv, 2023.12. 18.572108, 2023 | 1 | 2023 |
| Methods for treating cryptosporidiosis using triazolopyridazines CD Huston, K Bessoff, RS Jumani US Patent 11,229,649, 2022 | | 2022 |
| Bicyclic azetidines cure infection with the diarrheal pathogen Cryptosporidium in mice by inhibiting parasite phenylalanyl-tRNA synthetase S Vinayak, RS Jumani, P Miller, MM Hasan, BI McLeod, J Tandel, ... Science translational medicine 12 (563), 2020 | | 2020 |
