Zuguang Gu
Zuguang Gu
National Center for Tumor Diseases, German Cancer Research Center, Heidelberg, Germany
Verified email at - Homepage
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Complex heatmaps reveal patterns and correlations in multidimensional genomic data
Z Gu, R Eils, M Schlesner
Bioinformatics 32 (18), 2847-2849, 2016
" Circlize" implements and enhances circular visualization in R
Z Gu, L Gu, R Eils, M Schlesner, B Brors
The whole-genome landscape of medulloblastoma subtypes
PA Northcott, I Buchhalter, AS Morrissy, V Hovestadt, J Weischenfeldt, ...
Nature 547 (7663), 311-317, 2017
Mutations in the SIX1/2 pathway and the DROSHA/DGCR8 miRNA microprocessor complex underlie high-risk blastemal type Wilms tumors
J Wegert, N Ishaque, R Vardapour, C Geörg, Z Gu, M Bieg, B Ziegler, ...
Cancer cell 27 (2), 298-311, 2015
Complex heatmap visualization
Z Gu
Imeta 1 (3), e43, 2022
Evolutionary trajectories of IDHWT glioblastomas reveal a common path of early tumorigenesis instigated years ahead of initial diagnosis
V Körber, J Yang, P Barah, Y Wu, D Stichel, Z Gu, MNC Fletcher, D Jones, ...
Cancer cell 35 (4), 692-704. e12, 2019
EnrichedHeatmap: an R/Bioconductor package for comprehensive visualization of genomic signal associations
Z Gu, R Eils, M Schlesner, N Ishaque
BMC genomics 19, 1-7, 2018
BAZ2A (TIP5) is involved in epigenetic alterations in prostate cancer and its overexpression predicts disease recurrence
L Gu, SC Frommel, CC Oakes, R Simon, K Grupp, CY Gerig, D Bär, ...
Nature genetics 47 (1), 22-30, 2015
Environment‐induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children
T Bauer, S Trump, N Ishaque, L Thürmann, L Gu, M Bauer, M Bieg, Z Gu, ...
Molecular Systems Biology 12 (3), 861, 2016
Whole genome sequencing puts forward hypotheses on metastasis evolution and therapy in colorectal cancer
N Ishaque, ML Abba, C Hauser, N Patil, N Paramasivam, ...
Nature communications 9 (1), 4782, 2018
Hypoxia induces PGC-1α expression and mitochondrial biogenesis in the myocardium of TOF patients
L Zhu, Q Wang, L Zhang, Z Fang, F Zhao, Z Lv, Z Gu, J Zhang, J Wang, ...
Cell research 20 (6), 676-687, 2010
RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia
DB Lipka, T Witte, R Toth, J Yang, M Wiesenfarth, P Nöllke, A Fischer, ...
Nature communications 8 (1), 2126, 2017
simplifyEnrichment: an R/Bioconductor package for clustering and visualizing functional enrichment results
Z Gu, D Hübschmann
Genomics, Proteomics & Bioinformatics, 2022
Memory-like HCV-specific CD8+ T cells retain a molecular scar after cure of chronic HCV infection
N Hensel, Z Gu, Sagar, D Wieland, K Jechow, J Kemming, ...
Nature immunology 22 (2), 229-239, 2021
Centrality-based pathway enrichment: a systematic approach for finding significant pathways dominated by key genes
Z Gu, J Liu, K Cao, J Zhang, J Wang
BMC systems biology 6, 1-13, 2012
Make Interactive Complex Heatmaps in R
Z Gu, D Hübschmann
Bioinformatics, 2021
Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell of origin
E Espinet, Z Gu, CD Imbusch, NA Giese, M Büscher, M Safavi, ...
Cancer discovery 11 (3), 638-659, 2021
Mutational patterns and regulatory networks in epigenetic subgroups of meningioma
N Paramasivam, D Hübschmann, UH Toprak, N Ishaque, M Neidert, ...
Acta neuropathologica 138, 295-308, 2019
Prenatal maternal stress and wheeze in children: novel insights into epigenetic regulation
S Trump, M Bieg, Z Gu, L Thürmann, T Bauer, M Bauer, N Ishaque, ...
Scientific reports 6 (1), 28616, 2016
Quantitative proteomics reveals specific metabolic features of acute myeloid leukemia stem cells
S Raffel, D Klimmeck, M Falcone, A Demir, A Pouya, P Zeisberger, C Lutz, ...
Blood, The Journal of the American Society of Hematology 136 (13), 1507-1519, 2020
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