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Alicia Solorzano
Alicia Solorzano
Director, Viral Vaccines, Pfizer
Bestätigte E-Mail-Adresse bei pfizer.com
Titel
Zitiert von
Zitiert von
Jahr
Characterization of the reconstructed 1918 Spanish influenza pandemic virus
TM Tumpey, CF Basler, PV Aguilar, H Zeng, A Solórzano, DE Swayne, ...
science 310 (5745), 77-80, 2005
18382005
A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission
TM Tumpey, TR Maines, N Van Hoeven, L Glaser, A Solórzano, C Pappas, ...
Science 315 (5812), 655-659, 2007
6902007
Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality …
TM Tumpey, A García-Sastre, JK Taubenberger, P Palese, DE Swayne, ...
Journal of virology 79 (23), 14933-14944, 2005
6642005
Mutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs
A Solórzano, RJ Webby, KM Lager, BH Janke, A García-Sastre, JA Richt
Journal of virology 79 (12), 7535-7543, 2005
3242005
Live attenuated influenza viruses containing NS1 truncations as vaccine candidates against H5N1 highly pathogenic avian influenza
J Steel, AC Lowen, L Pena, M Angel, A Solórzano, R Albrecht, DR Perez, ...
Journal of virology 83 (4), 1742-1753, 2009
2892009
Replication fitness determines high virulence of influenza A virus in mice carrying functional Mx1 resistance gene
D Grimm, P Staeheli, M Hufbauer, I Koerner, L Martínez-Sobrido, ...
Proceedings of the National Academy of Sciences 104 (16), 6806-6811, 2007
2502007
A chimeric hemagglutinin-based universal influenza virus vaccine approach induces broad and long-lasting immunity in a randomized, placebo-controlled phase I trial
R Nachbagauer, J Feser, A Naficy, DI Bernstein, J Guptill, EB Walter, ...
Nature medicine 27 (1), 106-114, 2021
2442021
Vaccination of pigs against swine influenza viruses by using an NS1-truncated modified live-virus vaccine
JA Richt, P Lekcharoensuk, KM Lager, AL Vincent, CM Loiacono, ...
Journal of virology 80 (22), 11009-11018, 2006
2242006
Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus
C Pappas, PV Aguilar, CF Basler, A Solórzano, H Zeng, LA Perrone, ...
Proceedings of the National Academy of Sciences 105 (8), 3064-3069, 2008
2142008
Influenza A(H7N9) virus gains neuraminidase inhibitor resistance without loss of in vivo virulence or transmissibility
R Hai, M Schmolke, VH Leyva-Grado, RR Thangavel, I Margine, EL Jaffe, ...
Nature communications 4 (1), 2854, 2013
1822013
A universal influenza virus vaccine candidate confers protection against pandemic H1N1 infection in preclinical ferret studies
R Nachbagauer, WC Liu, A Choi, TJ Wohlbold, T Atlas, M Rajendran, ...
npj Vaccines 2 (1), 26, 2017
1302017
Immunogenicity of chimeric haemagglutinin-based, universal influenza virus vaccine candidates: interim results of a randomised, placebo-controlled, phase 1 clinical trial
DI Bernstein, J Guptill, A Naficy, R Nachbagauer, F Berlanda-Scorza, ...
The lancet infectious diseases 20 (1), 80-91, 2020
1292020
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics
K Leppek, GW Byeon, W Kladwang, HK Wayment-Steele, CH Kerr, AF Xu, ...
Nature communications 13 (1), 1536, 2022
1262022
Hemagglutinin (HA) proteins from H1 and H3 serotypes of influenza A viruses require different antigen designs for the induction of optimal protective antibody responses as …
S Wang, J Taaffe, C Parker, A Solórzano, H Cao, A García-Sastre, S Lu
Journal of virology 80 (23), 11628-11637, 2006
1252006
Heterologous HA DNA vaccine prime—inactivated influenza vaccine boost is more effective than using DNA or inactivated vaccine alone in eliciting antibody responses against H1 …
S Wang, C Parker, J Taaffe, A Solórzano, A García-Sastre, S Lu
Vaccine 26 (29-30), 3626-3633, 2008
1132008
Functional genomic and serological analysis of the protective immune response resulting from vaccination of macaques with an NS1-truncated influenza virus
CR Baskin, H Bielefeldt-Ohmann, A Garcia-Sastre, TM Tumpey, ...
Journal of virology 81 (21), 11817-11827, 2007
1022007
Viral reassortment and transmission after co-infection of pigs with classical H1N1 and triple-reassortant H3N2 swine influenza viruses
W Ma, KM Lager, P Lekcharoensuk, ES Ulery, BH Janke, A Solorzano, ...
Journal of General Virology 91 (9), 2314-2321, 2010
702010
Alternative live-attenuated influenza vaccines based on modifications in the polymerase genes protect against epidemic and pandemic flu
A Solórzano, J Ye, DR Pérez
Journal of virology 84 (9), 4587-4596, 2010
682010
Sequential immunization with live-attenuated chimeric hemagglutinin-based vaccines confers heterosubtypic immunity against influenza A viruses in a preclinical ferret model
WC Liu, R Nachbagauer, D Stadlbauer, A Solórzano, F Berlanda-Scorza, ...
Frontiers in immunology 10, 450546, 2019
552019
An avian live attenuated master backbone for potential use in epidemic and pandemic influenza vaccines
D Hickman, MJ Hossain, H Song, Y Araya, A Solorzano, DR Perez
Journal of general virology 89 (11), 2682-2690, 2008
542008
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