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Manuel Merlos
Manuel Merlos
Head of Pharmacology
Bestätigte E-Mail-Adresse bei welab.barcelona
Titel
Zitiert von
Zitiert von
Jahr
Substituting walnuts for monounsaturated fat improves the serum lipid profile of hypercholesterolemic men and women: a randomized crossover trial
D Zambón, J Sabaté, S Munoz, B Campero, E Casals, M Merlos, ...
Annals of internal medicine 132 (7), 538-546, 2000
4782000
Oleate reverses palmitate-induced insulin resistance and inflammation in skeletal muscle cells
T Coll, E Eyre, R Rodríguez-Calvo, X Palomer, RM Sánchez, M Merlos, ...
Journal of biological chemistry 283 (17), 11107-11116, 2008
4212008
New Azole Antifungals. 3. Synthesis and Antifungal Activity of 3-Substituted-4(3H)-quinazolinones
J Bartroli, E Turmo, M Algueró, E Boncompte, ML Vericat, L Conte, ...
Journal of medicinal chemistry 41 (11), 1869-1882, 1998
2871998
Synthesis and SAR of a New Series of COX-2-Selective Inhibitors:  Pyrazolo[1,5-a]pyrimidines
C Almansa, AF de Arriba, FL Cavalcanti, LA Gómez, A Miralles, M Merlos, ...
Journal of medicinal chemistry 44 (3), 350-361, 2001
2332001
Palmitate induces tumor necrosis factor-α expression in C2C12 skeletal muscle cells by a mechanism involving protein kinase C and nuclear factor-κB activation
M Jové, A Planavila, RM Sánchez, M Merlos, JC Laguna, ...
Endocrinology 147 (1), 552-561, 2006
2172006
Pharmacological properties of S1RA, a new sigma‐1 receptor antagonist that inhibits neuropathic pain and activity‐induced spinal sensitization
L Romero, D Zamanillo, X Nadal, R Sánchez‐Arroyos, I Rivera‐Arconada, ...
British journal of pharmacology 166 (8), 2289-2306, 2012
2092012
Rupatadine, a new potent, orally active dual antagonist of histamine and platelet-activating factor (PAF)
M Merlos, M Giral, D Balsa, R Ferrando, M Queralt, A Puigdemont, ...
Journal of Pharmacology and Experimental Therapeutics 280 (1), 114-121, 1997
1951997
Palmitate-mediated downregulation of peroxisome proliferator–activated receptor-γ coactivator 1α in skeletal muscle cells involves MEK1/2 and nuclear factor-κB activation
T Coll, M Jové, R Rodríguez-Calvo, E Eyre, X Palomer, RM Sánchez, ...
Diabetes 55 (10), 2779-2787, 2006
1822006
Synthesis and structure− activity relationship of a new series of COX-2 selective inhibitors: 1, 5-diarylimidazoles
C Almansa, J Alfón, AF de Arriba, FL Cavalcanti, I Escamilla, LA Gómez, ...
Journal of medicinal chemistry 46 (16), 3463-3475, 2003
1782003
Sigma 1 receptor: a new therapeutic target for pain
D Zamanillo, L Romero, M Merlos, JM Vela
European Journal of Pharmacology 716 (1-3), 78-93, 2013
1572013
Activation of peroxisome proliferator–activated receptor β/δ inhibits lipopolysaccharide-induced cytokine production in adipocytes by lowering nuclear factor-κB activity via …
R Rodriguez-Calvo, L Serrano, T Coll, N Moullan, RM Sánchez, M Merlos, ...
Diabetes 57 (8), 2149-2157, 2008
1522008
Synthesis and Biological Evaluation of the 1-Arylpyrazole Class of σ1 Receptor Antagonists: Identification of 4-{2-[5-Methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yloxy …
JL Díaz, R Cuberes, J Berrocal, M Contijoch, U Christmann, A Fernández, ...
Journal of medicinal chemistry 55 (19), 8211-8224, 2012
1412012
Rupatadine: a new selective histamine H1 receptor and platelet-activating factor (PAF) antagonist. A review of pharmacological profile and clinical management of allergic rhinitis.
I Izquierdo, M Merlos, J García-Rafanell
Drugs of today (Barcelona, Spain: 1998) 39 (6), 451-468, 2003
1232003
PPARβ/δ activation blocks lipid-induced inflammatory pathways in mouse heart and human cardiac cells
D Álvarez-Guardia, X Palomer, T Coll, L Serrano, R Rodríguez-Calvo, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2011
992011
Reduction of liver fructokinase expression and improved hepatic inflammation and metabolism in liquid fructose-fed rats after atorvastatin treatment
L Vilà, A Rebollo, GS Ađalsteisson, M Alegret, M Merlos, N Roglans, ...
Toxicology and applied pharmacology 251 (1), 32-40, 2011
942011
Sigma-1 receptor antagonism as opioid adjuvant strategy: enhancement of opioid antinociception without increasing adverse effects
A Vidal-Torres, B De La Puente, M Rocasalbas, C Touriño, SA Bura, ...
European journal of pharmacology 711 (1-3), 63-72, 2013
932013
Endocannabinoid control of glutamate NMDA receptors: the therapeutic potential and consequences of dysfunction
M Rodríguez-Muñoz, P Sánchez-Blázquez, M Merlos, J Garzón-Niño
Oncotarget 7 (34), 55840, 2016
902016
Modulation of peripheral μ-opioid analgesia by σ1 receptors
C Sánchez-Fernández, Á Montilla-García, R González-Cano, FR Nieto, ...
Journal of Pharmacology and Experimental Therapeutics 348 (1), 32-45, 2014
892014
The σ1 receptor engages the redox-regulated HINT1 protein to bring opioid analgesia under NMDA receptor negative control
M Rodríguez-Muñoz, P Sánchez-Blázquez, R Herrero-Labrador, ...
Antioxidants & redox signaling 22 (10), 799-818, 2015
842015
Walnut-enriched diet increases the association of LDL from hypercholesterolemic men with human HepG2 cells
S Muñoz, M Merlos, D Zambón, C Rodríguez, J Sabaté, E Ros, ...
Journal of lipid research 42 (12), 2069-2076, 2001
842001
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