Opioid receptors: drivers to addiction? E Darcq, BL Kieffer Nature Reviews Neuroscience 19 (8), 499-514, 2018 | 295 | 2018 |
Translating the habenula—from rodents to humans LJ Boulos, E Darcq, BL Kieffer Biological psychiatry 81 (4), 296-305, 2017 | 158 | 2017 |
Chromatin remodeling—a novel strategy to control excessive alcohol drinking V Warnault, E Darcq, A Levine, S Barak, D Ron Translational psychiatry 3 (2), e231-e231, 2013 | 152 | 2013 |
Impaired emotional-like behavior and serotonergic function during protracted abstinence from chronic morphine C Goeldner, PE Lutz, E Darcq, T Halter, D Clesse, AM Ouagazzal, ... Biological psychiatry 69 (3), 236-244, 2011 | 149 | 2011 |
MicroRNA-30a-5p in the prefrontal cortex controls the transition from moderate to excessive alcohol consumption E Darcq, V Warnault, K Phamluong, GM Besserer, F Liu, D Ron Molecular psychiatry 20 (10), 1240-1250, 2015 | 119 | 2015 |
Ethanol-mediated facilitation of AMPA receptor function in the dorsomedial striatum: implications for alcohol drinking behavior J Wang, SB Hamida, E Darcq, W Zhu, SL Gibb, MF Lanfranco, ... Journal of Neuroscience 32 (43), 15124-15132, 2012 | 98 | 2012 |
The BDNF valine 68 to methionine polymorphism increases compulsive alcohol drinking in mice that is reversed by tropomyosin receptor kinase B activation V Warnault, E Darcq, N Morisot, K Phamluong, L Wilbrecht, SM Massa, ... Biological psychiatry 79 (6), 463-473, 2016 | 94 | 2016 |
Mu‐opioid receptor activation induces transcriptional plasticity in the central extended amygdala K Befort, D Filliol, A Ghate, E Darcq, A Matifas, J Muller, A Lardenois, ... European Journal of Neuroscience 27 (11), 2973-2984, 2008 | 90 | 2008 |
Deletion of the mu opioid receptor gene in mice reshapes the reward–aversion connectome AE Mechling, T Arefin, HL Lee, T Bienert, M Reisert, S Ben Hamida, ... Proceedings of the National Academy of Sciences 113 (41), 11603-11608, 2016 | 83 | 2016 |
Control of aversion by glycine-gated GluN1/GluN3A NMDA receptors in the adult medial habenula Y Otsu, E Darcq, K Pietrajtis, F Mátyás, E Schwartz, T Bessaih, ... Science 366 (6462), 250-254, 2019 | 75 | 2019 |
Mu opioid receptors in gamma-aminobutyric acidergic forebrain neurons moderate motivation for heroin and palatable food P Charbogne, O Gardon, E Martín-García, HL Keyworth, A Matsui, ... Biological psychiatry 81 (9), 778-788, 2017 | 75 | 2017 |
Biased signaling of the mu opioid receptor revealed in native neurons AT Ehrlich, M Semache, F Gross, DF Da Fonte, L Runtz, C Colley, ... IScience 14, 47-57, 2019 | 66 | 2019 |
Protracted abstinence from distinct drugs of abuse shows regulation of a common gene network J Le Merrer, K Befort, O Gardon, D Filliol, E Darcq, D Dembele, ... Addiction biology 17 (1), 1-12, 2012 | 64 | 2012 |
The negative affect of protracted opioid abstinence: progress and perspectives from rodent models L Welsch, J Bailly, E Darcq, BL Kieffer Biological psychiatry 87 (1), 54-63, 2020 | 63 | 2020 |
Delta opioid receptors expressed in forebrain GABAergic neurons are responsible for SNC80-induced seizures PCS Chung, A Boehrer, A Stephan, A Matifas, G Scherrer, E Darcq, ... Behavioural brain research 278, 429-434, 2015 | 63 | 2015 |
Mu opioid receptors in the medial habenula contribute to naloxone aversion LJ Boulos, S Ben Hamida, J Bailly, M Maitra, AT Ehrlich, C Gaveriaux-Ruff, ... Neuropsychopharmacology 45 (2), 247-255, 2020 | 58 | 2020 |
Expression map of 78 brain-expressed mouse orphan GPCRs provides a translational resource for neuropsychiatric research AT Ehrlich, G Maroteaux, A Robe, L Venteo, MT Nasseef, LC van Kempen, ... Communications Biology 1 (1), 102, 2018 | 53 | 2018 |
Current strategies toward safer mu opioid receptor drugs for pain management AT Ehrlich, BL Kieffer, E Darcq Expert opinion on therapeutic targets 23 (4), 315-326, 2019 | 51 | 2019 |
Increased alcohol seeking in mice lacking Gpr88 involves dysfunctional mesocorticolimbic networks SB Hamida, S Mendonça-Netto, TM Arefin, MT Nasseef, LJ Boulos, ... Biological psychiatry 84 (3), 202-212, 2018 | 46 | 2018 |
The neurotrophic factor receptor p75 in the rat dorsolateral striatum drives excessive alcohol drinking E Darcq, N Morisot, K Phamluong, V Warnault, J Jeanblanc, FM Longo, ... Journal of Neuroscience 36 (39), 10116-10127, 2016 | 43 | 2016 |